Is INmune Bio On The Verge Of Making Big Market Moves?


A couple of BIG developments show us that smart money seems to think so.

INmune Bio (NASDAQ:INMB) Closes Private Placement of Approximately $4.1 Million of Common Stock, Led by Insiders and Existing Shareholders At $9.00 a share Source

INmune Bio Announces Common Stock Purchase Agreement for up to $20.0 Million with Lincoln Park Capital Source

The growing interest in newly listed INmune Bio (NASDAQ:INMB) is primarily due to its 3 promising therapies all in various stages of clinical development. 

XPro1595 is a one of a kind Alzheimer’s therapy and will be enrolling patients into a Phase 1 trial this summer. INmune Bio believes inflammation is the cause of Alzheimer’s and thinks Xpro1595 can slow the progress of Alzheimers. This product is a very big deal right now for the Alzheimer drug market.

The other 2 products, INBO3 already has impressive Phase 1 data and is entering Phase 2 clinical trials.
INKmune is entering phase 1 clinical trials, both drugs are designed to supercharge the immunesystem to target and fight cancer;

Lets talk about the potentially game changing Alzheimer and dementia product first: XPpro1595

  • In early 2019, INmune Bio received validation with a $1,000,000 grant funding from the US Alzheimer’s Association to develop this drug.
  • There are over 5.8 million Americans living with Alzheimer’s Disease and other dementias at a cost to the healthcare system of $290 billion dollars. Within 30 years, that figure is estimated to grow to $1.1 trillion dollars as the number of patients rises to 14 million.
  • Alzheimer’s is the 6th leading cause of death in the United States and 16 million people are providing uncompensated care for those afflicted. The current value of the uncompensated care (usually family members) is $234 billion.
  • Big pharma has been spending billions developing the wrong Alzheimer’s therapies that focused on treating the disease with an approach many believed would work but proved wrong with bad phase 3 data.
  • Any promising ll Alzheimer drugs that were in mid to late-stage development have stopped. The drug companies approached Alzheimer’s the same way, Amyloid, the build up of fatal proteins. And they failed Source:

This means INmune Bio’s approach to treating the disease by stopping the progression of inflammation could the only promising, next generation Alzheimer drug in development. They are the new kids on the block and entering the clinic!!

We know big pharma likes to acquire the little guys: Because of these failures… wouldn’t it be likely that biopharma buys a small biotech that shows any promising signs of good clinical data in Alzheimer?

The Other Side Of The System

To put it simply, INmune Bio is looking where nobody else is. The company is It’s focused on stopping inflammation to treat Alzheimers and harnessing the other side of the immune system to fight Cancer – the innate immune side.

Most people don’t realize that the human body’s immune system has two sides – essentially two immune systems. The adaptive side responds to foreign substances that enter the body; the innate side of the system deals with bad things that are already there.

And because many cancers develop from pre-cancerous cells that are created by the body, the adaptive immune system gives them a pass. Fortunately, the innate system doesn’t.

Its cells seek out and kill these abnormal cells. Which is why they’re called
Natural Killer Cells.

But sometimes these Natural Killer can’t do their job because cancer cells have the uncanny ability to make themselves virtually invisible. Especially those cancer cells left in the body after treatment. INmune Bio solution to the problem is a new product called INKmune™
INKmune™ programs the NK cells to identify these cloaked cancer cells and kill them. Which makes INKmune unlike any other cancer therapy in the world.

INKmune™ is currently approved for Phase 1 clinical trials  and will start enrolling patients soon in Great Britain. Watch this amazing short video we found discussing operations with Prof. Mark Lowdell, INmune Bio’s CMO:

As much of a breakthrough as INKmune™ promises to be, it’s not the only cancer weapon in INmune Bio’s arsenal. Of equal importance is …

Cancer Weapons

One of the company’s two lead development products in the fight against cancer is INB03 – a protein biologic that works by inhibiting the activities of  Myeloid-Derived Suppressor Cells (MDSC). These cells create a shield around the patient’s tumor; INB03 strips away this shield so that the body’s Natural Killer cells can attack it.

INBO3 is part of a class of drugs known as checkpoint inhibitors – the market for which is said to be $1 Billion massive, over $47 billion globally in a few years. At present, existing drugs in this class work in only 25% of patients. If INBO3, proves effective, INmune Bio (NASDAQ:INMB) will likely dominate this market.

The other promising anti-cancer therapy is a product called INKmune™. It primes the body’s Natural Killer (NK) cells to attack cancer cells that might otherwise evade them – because of the uncanny ability of cancer cells to make themselves virtually invisible.

INKmune™ is expected to be especially important in destroying cancer cells left in the body after treatment by surgery or chemotherapy.

INmune Bio’s arsenal isn’t only for combatting cancer, however. It also contains a potential weapon against Alzheimers disease.

Through The Roof?

Should INmune Bio (NASDAQ:INMB) succeed in just one of its therapies, that’s where its stock would likely go. In biotech, it’s similar to when an oil company makes a discovery. The stocks go BIG.
But because stock in biotech companies can move on data alone, major movement could occur on the outcome of one of INmune Bio’s clinical trials for its therapies. And those are right around the corner.

How other micro-cap biotechs are faring?
It should be noted that all these companies are less developed than INMB and trading at billion dollar market caps. We expect INMB to surpass these other companies developing similar but less novel, advanced programs.

$FATE (Developing NK cell therapeutic drugs. Same stage as $INMB)

$DNLI (Developing Alzheimer drugs. Not in clinical stage)

$ALEC (Developing Alzheimer’s drug. Not in clinical stage)

INmune Bio announced very good Phase 1 data for INBO3 was announced and Phase 2 clinical trials are starting!
INKmune™ phase 1 trials are enrollment is soon are due soon. And enrollment in Phase 1 trials for XPR01595 is also set for this summer.

An Acquisition Magnet?

INmune Bio (NASDAQ:INMB) would also become a prime target for a buy out. Small, agile biotech companies that are developing disruptive technologies like INmune Bio are always targets for big pharma.

INmune Bio to begin enrolling patients in Alzheimer’s study by mid-summer

Big pharmaceutical companies don’t innovate – they acquire.

Xencor (XNCR), a pioneer in antibody drugs and INmune Bio’s largest shareholder, has an option to buy another 10% of the company could likely opt for the rest of it. Unless, of course, another deep-pocketed, big pharma company gets there first.

Billion Dollar Buyouts

There’ve been a lot of those in the immune-oncology space lately.

  • – In 2017, Gilead (GILD) bought Kite Pharma (KITE) in a $11.9 Billion deal.
  • Celgene (CELG) acquired Juno (JUNO) for $9 Billion last year.
  • – This year, Bristol-Myers Squibb (BMY) bought Celgene in a $74 Billion deal.
  • And Eli Lilly (LLY) paid close to $8 Billion for Loxo Oncology (LOXO.)

All of the companies bought were developing therapies and were acquired Pre-FDA approval. And every one was working along adaptive immune-oncology lines. Which, so far, haven’t worked.

Just imagine what big pharma would pay for a biotech with a therapy that did?

All of which in our opinion, makes INmune Bio (INMB) an immediate and unequivocal “buy.” But you might want to act fast. Before big pharma gets there.

More Than Making Money

This is one of those rare cases where there’s something even more important than that…

For if even one of the company’s new products proves safe and effective, the treatment of cancer or Alzheimer’s and the lives of millions of people would be forever changed. And the world would be changed … for the better.

If you’d like to be a part of that, while making a lot of money, we’d suggest you start researching INmune Bio now!

For more information on INmuneBio’s (INMB), visit the company’s website and corporate presentation:

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